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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP1 All Species: 13.64
Human Site: S324 Identified Species: 25
UniProt: Q00013 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00013 NP_002427.1 466 52296 S324 T T R P P R K S E E D G K E Y
Chimpanzee Pan troglodytes XP_001143670 466 52277 S324 T T R P P R K S E E D G K E Y
Rhesus Macaque Macaca mulatta XP_001097559 469 52568 S324 T T R P P R K S E E D G K E Y
Dog Lupus familis XP_855454 544 60389 G402 T T R P P K K G E E D G K E Y
Cat Felis silvestris
Mouse Mus musculus P70290 466 52209 S324 T T R P P K K S E E D G K E Y
Rat Rattus norvegicus Q62915 909 103240 D764 T T R P P K K D E E N G K N Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513222 468 52731 N326 T T R P P K K N E V D G K E Y
Chicken Gallus gallus Q5ZJ00 468 52501 N326 T T R P Q K K N E V D G K D Y
Frog Xenopus laevis NP_001079689 460 51420 G319 T S R P P K R G E E E S G S Y
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 Q410 T S R S K R H Q E S E G V E Y
Tiger Blowfish Takifugu rubipres P49697 467 52590 G325 T T R P Q R K G D A N G E E Y
Fruit Fly Dros. melanogaster Q24210 898 100893 E753 T T R P A K P E E E N G R S Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54936 961 108794 D816 T T R P P R K D E V D G K H Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.4 80.3 N.A. 92.9 32.8 N.A. 85.9 83.1 66.7 32.2 63.3 30.7 N.A. 26.9 N.A.
Protein Similarity: 100 100 98.2 82.9 N.A. 95 42.9 N.A. 92.7 92.5 80.6 49.4 77.7 41.2 N.A. 37.3 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 73.3 N.A. 80 66.6 46.6 46.6 60 53.3 N.A. 80 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 86.6 N.A. 93.3 86.6 73.3 60 80 73.3 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 16 8 0 62 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 8 93 62 16 0 8 62 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 24 0 0 0 93 8 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 54 77 0 0 0 0 0 70 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 0 24 0 0 8 0 % N
% Pro: 0 0 0 93 70 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 16 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 47 8 0 0 0 0 0 8 0 0 % R
% Ser: 0 16 0 8 0 0 0 31 0 8 0 8 0 16 0 % S
% Thr: 100 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 24 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _